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They rub their muzzles against the ground, various hard objects, and limbs. In order for the larva to emerge from the egg, its surface must be wetted, which occurs during watering or lip licking. The larvae that did not leave the egg die after 4 days, and those that hatched, getting into the oral cavity, attach to the mucous membrane and develop until molting and transition to the 2nd stage, after which they enter the stomach. Before entering pupation, the larvae of the 3rd stage are fixed in the rectum, where they finally mature and are excreted into the external environment with faeces. The pupal phase lasts 16-20 days.

Zofran pills - black-brown, almost black, 12 - 13 mm long. Head narrower than mesoscutum, anteriorly yellowish-brown with a reddish tint, crown dark. Brown hairs on back of head. The chest is black, with hairs. Wings 9 - 10 mm long, wide, transparent with yellowish veins, without spots. The color of the legs is from black to brown, in patches light brown. The abdomen is black to brown, covered with dense hairs. Egg 1.29 mm long, yellowish with structural transverse lines and a small round lid.

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Larva of the 1st stage 1.48 mm long and 0.2 mm wide with long thin horny hooks. On the sides of the segments are long bristles. A characteristic feature of the larva is the long setae directed backwards on the thoracic and first 7 abdominal segments. Larva of the 2nd stage up to 11 mm long and 2.5 mm wide, somewhat narrower in front and slightly swollen behind. Mouth hooks thin, long. Larva of the 3rd stage up to 20 mm long, spines on segments arranged in one row.

The gadfly larva parasitizes horses and donkeys. Its years in most of the territory of Russia take place in June - August. Gadfly females lay their eggs on the basal part of the hair in the intermaxillary space, rarely on the neck. The larva of the 1st stage emerges from the eggs, crawls along the surface of the skin to the lips, penetrates into the mouth and develops in the gums of the host within 18-24 days. Larvae of the 2nd and 3rd stages are located in the duodenum. In the spring, they come out, pupate, and after 16-24 days, an adult gadfly emerges from the pupa.

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    ondansetron - females are dark brown, 16mm long, males are slightly lighter, 13mm long. The head is slightly narrower than the chest, the forehead is narrow. Its front part is yellow-brown, behind it is dark brown, covered with dense long shaggy hairs. Thorax brown, mesoscutum black with two longitudinal lighter stripes. Abdomen dark brown, wider than thorax. Legs are brownish-yellow. Black egg 0.90 mm long, with a large oval lid.

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    Larva of ondansetron stage 0.90 - 0.95 mm long, white, with strongly curved ends of the mouth hooks. Larva of the 2nd stage 12 mm long. The mouth hooks are strongly bent and their apices approach the base. The spines on the segments are very large. Larva of the 3rd stage up to 20 mm in length. It differs from other species of the genus by the presence of a median group of spines on the pseudocephalus. Mouth hooks are large, with a massive base. Spines of first row on segments twice as large as those of second row.

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    Having flown up to the tip of the leaf, it hangs in the air and, holding on to the edge of the leaf, attaches 6–10 eggs to it for 30 seconds. Then flies to a new placeThat. The life expectancy of a female is 1–2 days, therefore, during this time, the entire supply of eggs is consumed, and laying is carried out in 150–300 places. The animal becomes infected by eating grass with eggs laid on it. In 5 - 8 days after laying, larvae are formed in the eggs, which, in sodium eggs, can remain viable for up to 9 months and endure winter frosts.

When an egg enters the oral cavity of the host, the larva leaves it, penetrates into the oral mucosa and migrates in the tissues towards the soft palate. Larvae of the 2nd and 3rd stage live in the stomach, and only a small part of them lives in the oral cavity and ondansetron pills. Before entering pupation, the larvae attach themselves to the rectal mucosa for several days and acquire a greenish color here. The larvae that come out with feces pupate directly in them or in the ground in an upright position.

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Gadfly larvae parasitize in the digestive tract of the horse. The years of the gadfly with a temperate climate begin in July. G. nigricornis - grayish-yellow color, medium size - body length 10 - 11mm. Wings 9 - 10 mm long, transparent, with brownish-yellow veins. The head is narrower than the thorax, covered with dense pale yellow hairs. The thorax and abdomen are black, covered with gray-yellow hairs. Behind the abdomen is rounded. Legs with light or dark brown femora and yellow lower legs and tarsi.

The larva of the 1st stage at hatching is 0.8 mm long and 0.14 mm wide. It differs from other larvae of the genus by the presence of long bristles on the body. Larvae of the 2nd stage and 16 mm in length, according to take ondansetron of the body and the arrangement of two rows of spines on most segments. But in the chernous, the armament of the last segments is stronger, and the slits of the posterior spiracles are short and wide. Larvae of the 3rd stage are up to 21.5 mm long, the first thoracic segment is cylindrical, which distinguishes the larvae of other species of the genus.

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The larva parasitizes in the duodenum of a horse. Flying gadfly occurs in April - May. The fertility of the female is 300 - 350 eggs. The female quickly flies up to buy zofran pills, lays eggs on the surface of the hair of the cheeks or carrying eggs, and just as quickly flies away. The animal reacts strongly to the approach of a gadfly - they shake their heads, kick them, rub their heads on their legs or on the ground. The larvae emerge after 3-5 days. They penetrate into the skin, making passages in it and moving to the corners of the mouth, then live in the mucous membrane of the cheeks for 20-30 days.

The larva of the 2nd stage is introduced into the wall of the duodenum so that only their posterior end remains on the surface. The internal lumen of the intestine narrows and intestinal obstruction may occur. Larvae of the 3rd stage have a greenish color. The use of detomidine hydrochloride in the in vivo study of larvae of the first stage of development, during their migration to the tongue of the horse.

  • The anesthetic detomidine hydrochloride, a synthetic a-2-adrenergic agonist, was used to examine the horse's oral cavity while studying the in vivo activity of the large and gastric gadfly during its migration into the horse's tongue.
  • Detomidine hydrochloride was administered to 2 horses in a pasture that had been attacked by a gadfly for 7 days. The drug was administered at a dose of 0.9 ml (90 μg) per 500 kg of live weight, and after 5 minutes analgesia occurred.
  • Animals remained calm during this procedure, which made it possible to closely examine and photograph tissue disorders caused by larvae of the 1st stage: fistulas, minor cavities, passages and traces of movement of larvae in the tongue.
  • Preliminary results of the study show that the length of the strokes can approximately double within 2 days from 4 to 8mm. Using this approach, it was determined that G. intestinalis larvae were absent in the mucous membrane of the buccal region of the oral cavity, even if there were a large number of them in the tongue.
  • It is concluded that detomidine hydrochloride can be used to examine the oral zofran of live horses and determine the effectiveness of various preventive measures against 1st stage larvae, which avoids the need to slaughter the horse. (Demidova L.D.).